Research

My research spans a broad range of topics and disciplines, from chemistry to materials science engineering and biomedical engineering. My research has been focused on better understanding and improving both human and environmental health.

Hydrogel formulations for sustained-release of broadly neutralizing antibodies

Jons, C. K.; Kasse, C. M.; Mayer, B. T.; Hyrien, O.; Sen, S., Meany, E. L.; d'Aquino, A. I.; Ganesh, P.; Eckman, N.; Dong, C.; Yan, J.; Nguyen, L. T.; Doulames, V. M.; Song, Y. E.; Saouaf, O. M.; Williams, C. M.; Williams, S. C.; Paredes, J.; Raghavan, R.; Palomares, M.; Appel, E. A.

Journal of Controlled Release, 2025

Metal–organic framework nanoparticles (Advanced Materials, 2018)

Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors (Science Advances, 2022)

Hydrogel‐based slow release of a receptor‐binding domain subunit vaccine elicits neutralizing antibody responses against SARS‐CoV‐2 (Advanced Materials, 2021)

Highly-active nickel phosphide hydrotreating catalysts prepared in situ using nickel hypophosphite precursors (Journal of Catalysis, 2016)

Reversible and selective encapsulation of dextromethorphan and β-estradiol using an asymmetric molecular capsule assembled via the weak-link approach (Journal of the American Chemical Society, 2017)

Engineering biopharmaceutical formulations to improve diabetes management (Science Translational Medicine, 2021)

Palladium (II) weak-link approach complexes bearing hemilabile N-heterocyclic carbene–thioether ligands (Inorganic Chemistry, 2017)

Effect of Particle Size on the Deep HDS Properties of Ni2P Catalysts (The Journal of Physical Chemistry C, 2019)

A redox-switchable, allosteric coordination complex (Journal of the American Chemical Society, 2018)

A concerted two-prong approach to the in situ allosteric regulation of bifunctional catalysis (Chemical Science, 2016)

An Allosterically Regulated, Four-State Macrocycle (Inorganic Chemistry, 2018)

Use of a biomimetic hydrogel depot technology for sustained delivery of GLP-1 receptor agonists reduces burden of diabetes management (Cell Reports Medicine, 2023)

Polyacrylamide‐based hydrogel coatings improve biocompatibility of implanted pump devices (Journal of Biomedical Materials Research Part A, 2023)

Infinite coordination polymer particles composed of stimuli-responsive coordination complex subunits (Chemistry of Materials, 2017)

Ultra‐Fast Insulin–Pramlintide Co‐Formulation for Improved Glucose Management in Diabetic Rats (Advanced Science, 2021)

Affinity-Directed Dynamics of Host–Guest Motifs for Pharmacokinetic Modulation viaSupramolecular PEGylation (Biomacromolecules, 2021)

Stable High‐Concentration Monoclonal Antibody Formulations Enabled by an Amphiphilic Copolymer Excipient (Advanced Therapeutics, 2023)

Water‐Enhancing Gels Exhibiting Heat‐Activated Formation of Silica Aerogels for Protection of Critical Infrastructure During Catastrophic Wildfire (Advanced Materials, 2024)

Multi-State Dynamic Coordination Complexes Interconverted through Counterion-Controlled Phase Transfer (Inorganic chemistry, 2021)

Biomimetic non-ergodic aging by dynamic-to-covalent transitions in physical hydrogels (ACS Applied Materials & Interfaces, 2024)

Structurally dynamic crystalline 1D coordination polymers enabled via the Weak-Link Approach (Polyhedron, 2022)

Sustained Delivery of GLP-1 Receptor Agonists from Injectable Biomimetic Hydrogels Improves Treatment of Diabetes (Cell Reports Medicine, 2023)

Tuning non-ergodic aging in hydrogels using environment-dependent interfacial chemistry (Bulletin of the American Physical Society, 2024)

Agent Orange and Narratives of Suffering (WWU Occam’s Razor, 2012)